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Posted by on May 20, 2015 in blog, Preventive Medicine | 0 comments



Typhoid fever is a life-threatening illness caused by a bacterium known as salmonella typhi. It usually spreads by the intake of food or water contaminated with faeces from a person infected with the bacteria. Pitiable living conditions and lack of hygiene and sanitation are the major factors that contribute to the spread of typhoid. Once ingested, the bacteria multiply in the intestine before entering the blood and spreading throughout the body.

“The first symptom of typhoid is very high fever reaching the temperature of 104°F.”

The first symptom of typhoid is very high fever reaching temperature of 104°F. Other symptoms include profuse sweating, abdominal discomfort and also diarrhoea. If not treated, it can also cause intestinal bleeding, infection of the brain, gall bladder, heart and bones and may even result in death.

Typhoid can be controlled by improving lifestyle conditions like hygiene and consuming uncontamined food. There are also vaccines available thanks to the advances in modern medicine that are very effective in preventing fever. Two types of vaccines are available. One is administered orally and contains live attenuated S.typhi. The other vaccine containing surface extracts of S.typhi bacteria, called Vi capsular polysaccharide, is administered directly into a muscle.

The Vi polysaccharide vaccine is considered safer and more effective compared to the other vaccines. There are two types of Vi capsular polysaccharide vaccines that are available. These are called Vi capsular polysaccharide and Vi capsular polysaccharide linked to tetanus toxoid (conjugate) vaccines. Vi conjugate vaccines incite the specialized cells in the human body known as T cells, which the Vi polysaccharide is not capable of doing alone.

The engagement of the T cells by the Vi conjugate vaccine improves the quality of antibodies in the body as well as how they respond to different ailments. Visit Apollo Clinics to get more information about the vaccines available and their effectiveness. These vaccines can be taken at an interval of three years for three years. The vaccine can be administered to infants above the age of six months, children between the ages of one to four years of age and also adults.

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